What is Peptide Therapy?
Peptide therapy is a modern medical approach that uses short chains of amino acids, known as peptides, to help treat various health conditions and enhance quality of life. Peptides can either be naturally occurring or produced synthetically and have the ability to influence biological processes in the body. They show promise across various medical fields like oncology, cardiology and antimicrobial treatments, indicating their potential to address a wide range of health issues with precision and efficacy.
Do Peptides Really Work?
The use of peptide therapy is supported by significant effectiveness in various clinical settings. Because peptide molecules are particularly beneficial for targeting specific protein-protein interactions within cells that are critical for numerous cellular functions, numerous clinical benefits have been noted across different therapeutic areas, including diabetes management and controlling diseases like HIV.
In the U.S. alone, there are more than 80 FDA-approved peptide medications, reflecting their significant therapeutic impact and potential benefits in clinical practice.
At Joy Wellness Partners (JWP), we’ve been at the forefront of peptide therapy since our founding in 2016, offering a range of peptide therapies tailored to individual needs. We’ve witnessed firsthand the benefits of several FDA-approved peptides in enhancing patients’ health and wellbeing.
How Much Do Peptide Injections Cost?
The cost of peptide therapy can vary widely, ranging from approximately $100 to $600 per month, depending on the specific peptide and treatment regimen. There are more oral formulations being developed, such as liposomal delivery systems; while these will be more affordable than injectable peptides, their effectiveness is yet to be determined.
Where and Why Are Peptides Injected?
Peptides are often injected because their molecular structure makes them susceptible to breakdown in the digestive system. Common routes of administration include subcutaneous, intramuscular or intravenous injections, depending on the desired absorption rate and therapeutic goals. These methods ensure that peptides reach their targeted areas within the body without degradation.
What is the Best Peptide for Anti-Aging?
Some peptides show potential in supporting anti-aging by enhancing mitochondrial function, but these are still under research and not yet FDA-approved. At JWP, we offer a range of longevity strategies, and we invite you to explore our memberships for more information.
Do I Need a Prescription for Peptides?
Yes, peptides generally require a prescription and should be administered under the guidance of a healthcare professional. It’s important to undergo proper evaluations, such as blood tests, to determine if peptide therapy is suitable for you.
How do I find safe peptide therapy near me?
Finding safe peptide therapy near you involves several important steps to ensure that you receive high-quality care from a reputable provider. Here’s how you can go about it:
1. Research Reputable Clinics:
- Search for Established Clinics: Look for well-established clinics with a good reputation for offering peptide therapy. Clinics that specialize in integrative or functional medicine often provide peptide therapies.
- Read Reviews and Testimonials: Check online reviews, testimonials, and ratings on platforms like Google, Yelp or the clinic’s website. Patient feedback can give you insights into the quality of care and the effectiveness of the treatments offered.
2. Verify Medical Credentials:
- Check the Credentials of Providers: Ensure that the clinic is staffed by licensed healthcare professionals, such as naturopathic medical doctors (NMDs), nurse practitioners (NPs) or medical doctors (MDs or DOs) who are experienced in peptide therapy.
- Board Certification: Preferably, choose providers who are board-certified in relevant fields such as endocrinology, integrative medicine or anti-aging medicine.
3. Consultation and Assessment:
- Schedule a Consultation: A reputable clinic should offer an initial consultation where you can discuss your health goals, medical history and the specific peptides that might be appropriate for you.
- Comprehensive Assessment: The clinic should perform a thorough assessment, including blood tests and other relevant diagnostics, to ensure that peptide therapy is safe and suitable for you.
4. Understand the Treatment Protocols:
- Inquire About Treatment Plans: Ask about the specific peptides they offer, the protocols they follow and the expected outcomes. The clinic should be transparent about the benefits and potential risks of the therapy.
- Personalized Treatment: Ensure that the therapy is personalized, based on your health needs, and that there’s a plan for monitoring and follow-up.
5. Check for FDA-Approved Peptides:
- FDA Approval: While many peptides used in therapy are not FDA-approved, some, like semaglutide, are. Verify which peptides the clinic uses and whether they are sourced from reputable, compounding pharmacies.
- Regulatory Compliance: Ensure that the clinic follows relevant regulatory guidelines for the administration of peptide therapies.
6. Consider the Cost:
- Transparent Pricing: A reputable clinic should provide clear information on the costs of peptide therapy, including any ongoing costs for follow-up appointments and monitoring.
- Payment Plans or FSA/HSA: Check if the clinic accepts FSA/HSA cards or if they offer payment plans, since peptide therapy can be expensive.
7. Location and Convenience:
- Proximity: Choose a clinic that is conveniently located, making it easier for you to keep regular appointments and follow-up visits.
- Accessibility: Ensure the clinic has good communication channels, allowing you to easily reach out to your provider for any concerns or questions that arise during your therapy.
8. Seek Recommendations:
- Ask for Referrals: If you know anyone who has undergone peptide therapy, ask them for recommendations. You can also ask your primary care physician for referrals to reputable clinics.
Online Communities: Engage in online health forums or communities where members share their experiences with peptide therapy and recommend trusted providers.
Example: Joy Wellness Partners
If you’re in Southern California or Southern Utah, Joy Wellness Partners clinics offer reputable peptide therapy. Established in 2016, Joy Wellness Partners have a proven track record of providing safe and effective peptide treatments tailored to individual needs through a multidisciplinary team of medical providers. You can learn more about their peptide offerings and book a consultation here.
By following these steps, you can find a safe and reputable clinic near you that offers peptide therapy in a manner that aligns with your health goals.
SPOTLIGHT ON SEMAGLUTIDE *
Is Ozempic (semaglutide) a Peptide?
Yes, Ozempic (semaglutide) is a peptide. It functions by activating glucagon-like peptide-1 receptors (GLP-1 AR), classifying it as a GLP-1 receptor agonist. Semaglutide mimics and amplifies the effects of the natural hormone GLP-1, which plays a crucial role in regulating glucose metabolism. Since its FDA approval, this peptide-based medication has gained significant attention for its ability to promote substantial weight loss. At Joy Wellness Partners, we’ve observed firsthand the remarkable and sustained results that semaglutide has delivered, surpassing those of any prior medical weight loss therapy we’ve offered.
What is the history of Ozempic?
Ozempic (Semaglutide), was first approved in the U.S. in 2017 to improve glycemic control in patients with Type 2 diabetes. Recently, higher doses of once-weekly semaglutide have proven effective for patients struggling with weight loss. The FDA now recognizes semaglutide as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in overweight or obese adults. A publication in the New England Journal of Medicine reported that more than 50% of participants in the STEP trial lost 15% of their body weight, and 33-40% lost 20%. GLP-1, a hormone produced in the small intestine, stimulates insulin secretion and inhibits glucagon secretion, effectively lowering blood sugar. This GLP-1 agonist also decreases appetite and reduces daily caloric intake, contributing to its efficacy in both glycemic control and weight management.
Are there other benefits of Semaglutide?
Semaglutide is effective not just for initial weight loss but also for maintaining weight loss over the long term. This is especially important for patients who struggle with obesity, as long-term weight management is crucial for reducing the risk of various health conditions, including Type 2 diabetes, hypertension and certain types of cancer.
In addition, semaglutide has shown the following benefits:
- Reduced Risk of Cardiovascular Events: Clinical trials, such as the SUSTAIN-6 study, have demonstrated that semaglutide significantly reduces the risk of major adverse cardiovascular events (MACE), including heart attack, stroke and cardiovascular death, in patients with Type 2 diabetes. This makes it particularly beneficial for those with a high risk of cardiovascular disease.
- Reduction in Triglycerides and LDL (“bad”) Cholesterol: Semaglutide has been associated with improvements in lipid profiles, including reductions in triglycerides and low-density lipoprotein (LDL) cholesterol. This further supports cardiovascular health and reduces the risk of atherosclerosis and heart disease.
- Reduction in Blood Pressure: Studies have shown that semaglutide can lead to modest reductions in both systolic and diastolic blood pressure (the top and bottom numbers on the blood pressure readings), which contributes to overall heart health.
- Reduction in Liver Fat: Preliminary studies suggest that semaglutide may help reduce liver fat content, which could be beneficial in managing or preventing non-alcoholic fatty liver disease (NAFLD), a common condition in individuals with obesity and Type 2 diabetes.
- Potential to Slow Progression of Diabetic Kidney Disease: Some studies have indicated that semaglutide may have protective effects on the kidneys, particularly in slowing the progression of diabetic kidney disease, which is a common complication of long-standing diabetes.
These benefits make semaglutide a powerful tool not only for managing diabetes and obesity, but also for providing broader health improvements that can significantly enhance the quality of life and reduce the risk of long-term complications.
Are There Risks of Ozempic (Semaglutide)?
Yes, there are risks with use of Ozempic, although the benefits of semaglutide generally outweigh the risks. As with use of any medication, it’s essential to be aware of the potential side effects of Ozempic, which may include nausea, constipation, acid reflux, stomach pain, vomiting and diarrhea. Patients with a history of hypoglycemia, kidney problems or allergic reactions may face an increased risk of serious side effects. It’s also advisable to pause semaglutide injections seven days before any surgery or procedures under general anesthesia. Semaglutide is contraindicated for individuals with Type 1 diabetes, a family history of Multiple Endocrine Neoplasia Syndrome Type 2 or Medullary Thyroid Cancer. If you have a history of pancreatitis, discuss with your provider before starting, as semaglutide can increase the risk of pancreatitis.
Conclusion
As the founder and first medical provider of Joy Wellness Partners, I have been spearheading the use of peptide therapy with our patients since 2016. Over the years, I have had the privilege of witnessing firsthand the transformative effects that peptides can have on our patients’ lives. For instance, immune-boosting peptides have significantly improved conditions like colitis, psoriasis, eczema, and Hashimoto’s. We’ve also seen remarkable success with semaglutide and tirzepatide, where patients have achieved significant weight loss without losing muscle mass, thanks to our integrated approach focusing on maintaining protein intake and optimizing hormone levels.
Additionally, the use of oxytocin has helped individuals develop deeper connections with their significant others and foster greater self-love. Another standout peptide, the Body Protecting Compound peptide, has been a life-changer for those struggling with heartburn, enabling them to taper off acid reflux medications and enjoy foods they never could before.
The potential of peptide therapy is immense, and our entire Joy Wellness Partners team is passionate about continuing to provide this cutting-edge treatment to help our patients achieve their health and wellness goals. mortality reduction?
Zone 2 training is associated with longevity and overall health benefits due to its positive effects on cardiovascular fitness and metabolic health. Regular aerobic exercise in Zone 2 improves cardiovascular function, reduces the risk of chronic diseases such as heart disease, diabetes and stroke, and enhances overall quality of life. Additionally, Zone 2 training promotes healthy aging by preserving muscle mass, maintaining cognitive function and supporting optimal physiological function throughout one’s lifespan. Incorporating Zone 2 training into one’s exercise routine is therefore essential for promoting longevity and maximizing overall health.
Sources:
- Alhayaza G, Enzmann MO, Yang M, Jain R, Weaver AL, Boos ST. Peptide Therapeutics for Osteoarthritis Treatment. J Immunol Res. 2022;2022:8844085. doi:10.1155/2022/8844085.
- Craik DJ, Fairlie DP, Liras S, Price D. The Future of Peptide-Based Drugs. Chem Biol Drug Des. 2013;81(1):136-147. doi:10.1111/cbdd.12055.
- Kovalainen M, Murtola TJ, Lahtinen M, et al. Peptides as Biomaterials for Drug Delivery. Adv Drug Deliv Rev. 2021;171:314-335. doi:10.1016/j.addr.2021.04.009.
- Lau JL, Dunn MK. Therapeutic peptides: Historical perspectives, current development trends, and future directions. Bioorg Med Chem. 2018;26(10):2700-2707. doi:10.1016/j.bmc.2017.06.052.
- Lichtenstein GR, Loftus EV, Isaacs KL, Regueiro MD, Gerson LB, Sands BE. A Practical Approach to the Safety and Monitoring of Therapeutic Peptides in the Management of Inflammatory Bowel Disease. Gastroenterology. 2016;151(4):1201-1210.e2. doi:10.1053/j.gastro.2016.08.010.
- Aroda VR, Ahmann A, Cariou B, et al. Comparative efficacy of semaglutide vs sitagliptin as add-on to metformin in subjects with type 2 diabetes. Lancet Diabetes Endocrinol. 2017;5(12):951-961. doi:10.1016/S2213-8587(17)30308-4.
- Marso SP, Bain SC, Consoli A, et al. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med. 2016;375(19):1834-1844. doi:10.1056/NEJMoa1607141.
- Wilding JPH, Batterham RL, Calanna S, et al. Once-weekly semaglutide in adults with overweight or obesity. N Engl J Med. 2021;384(11):989-1002. doi:10.1056/NEJMoa2032183.
- Davies MJ, Bergenstal R, Bode B, et al. Efficacy of liraglutide for weight loss among patients with type 2 diabetes: The SCALE diabetes randomized clinical trial. JAMA. 2015;314(7):687-699. doi:10.1001/jama.2015.9676. (Although this study focuses on liraglutide, it provides relevant insights on blood pressure improvement that can be extrapolated to semaglutide.)
- Lundgren JR, Janus C, Jensen SBK, et al. Healthy weight loss maintenance with exercise, liraglutide, or both combined. N Engl J Med. 2021;384(19):1719-1730. doi:10.1056/NEJMoa2028198. (This study examines liraglutide, the lipid-lowering effects are comparable with semaglutide.)
- Armstrong MJ, Gaunt P, Aithal GP, et al. Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): A multicentre, double-blind, randomised, placebo-controlled phase 2 study. Lancet. 2016;387(10019):679-690. doi:10.1016/S0140-6736(15)00803-X. (This study is based on liraglutide but provides insight into GLP-1 agonists, including semaglutide, and their impact on liver fat.)
- Mann JFE, Ørsted DD, Brown-Frandsen K, et al. Liraglutide and renal outcomes in type 2 diabetes. N Engl J Med.2017;377(9):839-848. doi:10.1056/NEJMoa1616011. (This study focuses on liraglutide but is relevant due to the class-wide effects seen with GLP-1 receptor agonists, including semaglutide.)
AUTHOR: Carol J Bender, Founder, NP, CEO Joy Wellness Partners